Skip to Main Content


Hospital to Home Transitions for the High-Risk Infant


When a “high-risk infant” who has spent the first weeks to months of his life in an intensive care nursery is preparing for discharge to the home environment, it does not matter whether the child was born extremely premature or at term with a complex list of medical diagnoses. While it seems obvious that a 600-g infant born at 25 weeks' gestation requires successful transition through several stages of maturation prior to being deemed ready for discharge, it is less recognized that a 4.5-kg infant born at 41 weeks' gestation with persistent pulmonary hypertension who required treatment with ECMO must satisfy many of the same requirements for discharge.


With advances in neonatal intensive care increasing survival rates for sicker newborns, a concomitant rise in complex morbidities present at the time of discharge has occurred. The process of moving from hospital to home will only be successful if it starts early and several transitions occur along the way. These transitions are not only required of the baby, but “minigraduations” must occur for the parents and providers as well.


I. Infant transitions


  1. Delivery room

    Successfully moving from the mother's womb to the outside world is required of all infants, whether they are admitted to the NICU or stay in the well-baby nursery. In the very low birthweight infant, “the golden hour” protocol of care along with the American Heart Association guidelines for neonatal resuscitation (NRP) has become a standard in the initial treatment of this high-risk population, in attempts to minimize the likelihood of poor long-term outcomes. This dogma, originating from the “golden hour of trauma,” suggests that the first hour of life in the sickest of neonates can have a lifetime impact. And, as the philosophy has been carried over to the treatment of adult patients with stroke and myocardial infarction, it is probably applicable not only for extremely preterm infants but also for very sick term infants who poorly transition in the delivery room. This critical hour of care starts in the DR and finishes in the NICU, and key areas of concern include those that, if not successfully addressed, could worsen acute stress.

    1. Appropriate resuscitation

    2. Maintenance of thermoregulation

    3. Treatment of sepsis

    4. Prevention of hypoglycemia

    5. Proper administration of fluids

    6. Completion of admission process

    This transition is accomplished through teamwork, consistency, and application of evidenced-based medicine. Along with the necessary individualization of care, proper support of this initial transition can significantly influence short-and long-term outcomes.

  2. Intensive to intermediate care

    Movement from neonatal intensive care to intermediate care requires that the infant meet several medical milestones. The baby must be medically ready for the next important transition.

    1. Minimum weight. Suggest 1200 g.

    2. Minimum gestational age. Suggest 32 weeks PMA.

    3. Minimal respiratory support required.

      1. Nasal cannula oxygen at most.

      2. Infants nearing discharge with a tracheostomy or requiring an increased level of respiratory support at baseline, but are stable, ...

Want remote access to your institution's subscription?

Sign in to your MyAccess profile while you are actively authenticated on this site via your institution (you will be able to verify this by looking at the top right corner of the screen - if you see your institution's name, you are authenticated). Once logged in to your MyAccess profile, you will be able to access your institution's subscription for 90 days from any location. You must be logged in while authenticated at least once every 90 days to maintain this remote access.


About MyAccess

If your institution subscribes to this resource, and you don't have a MyAccess profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus.

Subscription Options

AccessPediatrics Full Site: One-Year Subscription

Connect to the full suite of AccessPediatrics content and resources including 20+ textbooks such as Rudolph’s Pediatrics and The Pediatric Practice series, high-quality procedural videos, images, and animations, interactive board review, an integrated pediatric drug database, and more.

$595 USD
Buy Now

Pay Per View: Timed Access to all of AccessPediatrics

24 Hour Subscription $34.95

Buy Now

48 Hour Subscription $54.95

Buy Now

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.