ADEM in 4 different children.
A. A FLAIR image of a 2-year-old child with seizures shows peripheral lesions that involve cortical gray matter and subcortical white matter. There is also a lesion of the left caudate nucleus. B. There are bilateral thalamic lesions on this FLAIR image of a 3-year-old child. Additional areas of mild hyperintensity indicates widespread involvement of the basal ganglia, cortical gray matter, and subcortical white matter. C. Multiple well-defined hyperintense white matter foci are present on this T2-weighted image of a 6-year-old boy. D. This 2-year-old girl has extensive hyperintensity and enlargement of the thalami and basal ganglia.