• During standing, with decreased filling of ventricular chambers,
C-reactive fibers in myocardium are stimulated and initiate afferent
response to brain.
• In response, neural reflex is initiated with drop in blood pressure
or heart rate, or both.
• Patients with neurally mediated syncope have profound decrease
in blood pressure or heart rate or both, resulting in the following:
• Abdominal discomfort.
• Syncope (often).
• With profound hypotension or asystole, patient may experience
seizure due to cerebral hypoperfusion.