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I am pleased to present the sixth edition of Neonatology. Since the first edition was published in 1988, Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs continues to be widely accepted both in the United States and internationally. To date, various editions of this book have been translated into eight languages: Polish, Portuguese, Russian, Spanish, Yugoslavian, Turkish, Greek, and Chinese (short form). This worldwide acceptance is only made possible because of the contributions of our outstanding group of associate editors and contributors.

The specialty of neonatology continues to advance and the sixth edition has been completely updated to reflect the changes in our dynamic field. We have kept our basic format in this edition but changed most sections to alphabetical listings to make it easier to locate a chapter quickly. Section I, "Basic Management," is not alphabetical but is organized in a logical way with "Antepartum and Intrapartum Fetal Assessment" and "Obstetric Anesthesia" in the beginning and "Follow-up of High-Risk Infants" and "Neonatal Bioethics" at the end.

Some very interesting chapters are new to this edition. Section I now includes "Newborn Screening," which includes a discussion of some of the 29 screening tests recommended by the American College of Medical Genetics. Other additions include "Blood Component Therapy," "Management of the Late Preterm Infant," a relatively new area that focuses on the unique problems of late preterm infants, and "Complementary and Alternative Medical Therapies in Neonatology." Many families and practitioners are now interested in the complementary and alternative topic, another relatively new area in neonatology. The chapter includes a discussion of topics such as aromatherapy and sound and music therapy. "Defibrillation and Cardioversion" was added to the Procedure section and reviews indications and techniques.

The very popular and practical Section III, "On-Call Problems," was thoroughly updated and has the new chapter "Rash and Dermatologic Problems." The "On-Call Problems" continue to be the most popular and most commonly used section in the book. In Section IV, "Diseases and Disorders," the following sections are new: "Enteroviruses and Parechoviruses," "Eye Disorders of the Newborn and Retinopathy of Prematurity," "Methicillin-Resistant Staphylococcal Aureus (MRSA) Infections," "Orthopedic and Musculoskeletal Problems," "Parvovirus B19," "Ureaplasma Urealyticum Infections," and the new "Urologic Disorders".

Experienced users of the book will take note of the extensive revision and additions to Section V, "Neonatal Pharmacology." The sixth edition now contains one of the most comprehensive lists of neonatal medications available in a manual. We have combined the two tables on effects of drugs and substances taken during pregnancy and the effects of drugs and substances on breast-feeding to one table to make it more user friendly. The appendix has many new abbreviations, an updated blood pressure table to include very low birthweight infants, new growth charts, and a very useful isolation guideline table.

We are fortunate to have contributors from all over the United States with a good representation of all geographic regions. Contributors from Egypt, Finland, Australia and Canada help further internationalize the book. It is important to have many different centers represented because there are many different methods of caring for infants. Where appropriate, we have tried to include several different approaches to the management of the neonate. We recognize that some areas of neonatology are generally accepted as standard of care, whereas others are more controversial. The areas of controversy are noted as such in the text. For areas that are more controversial, it is always best to follow your local institutional guidelines.

I would like to thank Drs. Doug Cunningham and Fabien Eyal, my valued associate editors; Dr. Deborah Tuttle, consulting editor; Dr. Barbara McKinney; and all contributors to this and previous editions of the book. I also express my appreciation to Dr. Anne Sydor, Alyssa Fried, Harriet Lebowitz and the entire editorial and production staff at McGraw-Hill and their colleagues abroad for their extensive assistance during the two year journey to complete this edition. A special thanks to my husband, Lenny, who helped me extensively concerning matters of editorial content, and my children, Leonard, Patrick, Andrew, and Michael, who helped troubleshoot computer issues and tolerated many sacrifices while I worked on the book.

Lastly, I would like to acknowledge the origins of this book. The idea of the manual was developed during my neonatal fellowship at the University of Kentucky. I had the unique opportunity to finish my fellowship at Johns Hopkins University where I completed the project and added a new group of authors and ideas.

Any suggestions and comments about this manual are always welcome. Correspondence should be addressed to:

Tricia Lacy Gomella, MD
c/o McGraw-Hill Medical Publishers
Two Penn Plaza, 23th Floor
New York, NY 10121-2298
Tricia Lacy Gomella, MD
June, 2009

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