TY - CHAP M1 - Book, Section TI - Peripheral Nerve Disorders and Anterior Horn Cell Diseases A1 - Woodbury, Suzanne L. A1 - Collier, Talia A2 - Kline, Mark W. PY - 2018 T2 - Rudolph's Pediatrics, 23e AB - Diseases affecting the lower motor and sensory neurons can be classified by the area of pathologic involvement and are divided into 2 groups: anterior horn cell diseases and peripheral nerve disorders. Anterior horn cell (also known as motor neuron) diseases affect the most proximal portion of the motor unit and are primarily inherited or infectious. The spinal muscular atrophies are the major inherited disorders of the anterior horn cell. Infectious anterior horn cells disorders include paralytic poliomyelitis, which is largely eradicated from the Western world, in addition to other enterovirus, arbovirus, and West Nile virus. Peripheral nerve disorders affect the nerve segments distal to the anterior horn cell and may be divided into hereditary neuropathies and acquired neuropathies. Hereditary neuropathies (Charcot-Marie-Tooth) are more common in children than are acquired neuropathies. Acquired neuropathies include autoimmune inflammatory neuropathies such as Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy, facial neuropathies, infectious neuropathies, traumatic neuropathies, perinatal brachial plexus injuries, toxic neuropathies, and vitamin deficiency neuropathies. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182924023 ER -