TY - CHAP M1 - Book, Section TI - Childhood Tuberculosis A1 - Marais, Ben J. A2 - Shah, Samir S. A2 - Kemper, Alex R. A2 - Ratner, Adam J. PY - 2019 T2 - Pediatric Infectious Diseases: Essentials for Practice, 2e AB - Robert Koch (1843–1910) identified Mycobacterium tuberculosis as the cause of tuberculosis (TB) in 1882. It is now recognized that M. tuberculosis is an archetypical human pathogen and that its evolutionary origin is closely related to the controlled use of fire, which is unique to Homo sapiens and has created an environmental niche for mycobacteria to be transmitted via the respiratory route.1 This long period of coevolution explains why M. tuberculosis is so well adapted to its human host and why only a small minority of people infected with M. tuberculosis ever progress to active disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1157321978 ER -