TY - CHAP M1 - Book, Section TI - Chapter 231. Bacterial Infections of the Central Nervous System A1 - Murray, Thomas S. A1 - Baltimore, Robert S. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Meningitis, an infection of the subarachnoid space and leptomeninges caused by a variety of pathogenic organisms, continues to be an important source of mortality and morbidity. Despite the introduction of new vaccines that prevent the most severe causes, bacterial, or purulent, meningitis remains the most important form in the United States in terms of incidence, sequelae, and ultimate loss of productive life. Aseptic meningitis, usually caused by viruses, especially enteroviruses (see Chapter 306) is more common; however, significant sequelae are uncommon and the disease is usually self-limited. Granulomatous meningitis, caused either by M tuberculosis or fungi, is a major cause of neurologic injury and death in the developing world (See Chapter 269). SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7022283 ER -