TY  - CHAP
M1  - Book, Section
TI  - Chapter 296. Blastomycosis
A1  - Powell, Dwight A.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
PY  - 2011
T2  - Rudolph's Pediatrics, 22e
AB  - North  American  blastomycosis  is  a  pulmonary  or  disseminated  fungal  infection  caused  by  Blastomyces  dermatitidis.1,2  Although  rare  in  children,3  the  infection  is  often  difficult  to  detect  unless  considered  in  the  differential  diagnosis.  Blastomyces  dermatitidis  is  a  dimorphic  fungus  that  exists  as  a  mold  in  nature  and  is  generally  acquired  through  the  inhalation  of  spores  that  transform  to  yeast  in  the  lungs.  Although  isolation  from  natural  sources  has  been  very  difficult,  growth  appears  to  occur  in  acidic  soil  in  which  there  is  decaying  organic  matter  and  high  humidity.  Cases  of  blastomycosis  are  reported  from  other  countries  (particularly  those  in  central  Africa),  but  the  vast  majority  of  cases  have  occurred  in  the  Ohio  and  Mississippi  river  basins  and  the  southeastern  United  States.  The  highest  incidence  of  cases  appears  to  occur  in  Wisconsin,  Minnesota,  Mississippi,  Kentucky,  Tennessee,  and  Arkansas.  In  endemic  areas,  the  annual  incidence  of  symptomatic  infection  is  about  1  to  2  per  100,000  population.  Pockets  of  hyperendemic  regions  exist  where  the  annual  incidence  of  symptomatic  infection  may  approach  40  per  100,000  population.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7028768
ER  -