TY - CHAP M1 - Book, Section TI - Infectious Disease Issues in the NICU Graduate A1 - Malcolm, William F. PY - 2015 T2 - Beyond the NICU: Comprehensive Care of the High-Risk Infant AB - Infants can acquire infection prenatally through transplacental transfer, perinatally during birth, or postnatally. Newborn infants are relatively immunocompromised and at high risk of developing infections. The immune system of the newborn is immature and their skin, an important barrier to infection, is not fully developed. Infants admitted to the NICU often require invasive methods of support (eg, central venous lines or endotracheal tubes), which can serve as routes for infection. Infections result in significant mortality and both short- and long-term morbidities among survivors. In this chapter, we will discuss infections occurring in the newborn period, how these infections are treated, and long-term complications in survivors. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1105545504 ER -