TY - CHAP M1 - Book, Section TI - Congenital Abnormalities of the Brain A1 - Wells, Robert G. PY - 2015 T2 - Diagnostic Imaging of Infants and Children AB - The spectrum of congenital brain malformations is complex and classification schemes are imperfect. Neuroimaging evaluations provide extensive information concerning abnormal brain morphology and cellular organization. Correlation of this information with well-established concepts of normal embryological and fetal neural development provides a conceptual framework for a greater understanding of brain anomalies. The most frequently utilized neuroimaging classification scheme for congenital malformations of the brain recognizes 4 major types that correlate to stages of development: (1) dorsal induction (primary neurulation), (2) ventral induction (telencephalization), (3) neuronal proliferation, differentiation, and histogenesis, and (4) neuronal migration. It is important to recognize, however, that this system is an oversimplification of a heterogeneous and complex group of disorders. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1148948625 ER -