TY - CHAP M1 - Book, Section TI - Craniosynostosis A1 - Burrage, Lindsay C. A1 - Sutton, V. Reid A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - Craniosynostosis (also called craniostensosis) results from a premature fusion of the cranial sutures, which consist of fibrous connective tissue that connects the bones of the cranium. Craniosynostosis may occur as an isolated birth defect or as part of a syndrome. The major cranial sutures are the coronal sutures, which separate the frontal and parietal bones; the sagittal suture, which separates the parietal bones; the metopic suture, which separates the frontal bones; and the lambdoid sutures, which separate the parietal and occipital bones. The main functions of these sutures is to facilitate deformation of the skull during passage through the birth canal and to facilitate growth of the cranium to accommodate rapid brain growth during early childhood. Typically, cranial sutures close in early adulthood with the exception of the metopic suture, which closes in early childhood. Craniosynostosis may affect 1 or more of these sutures, and premature fusion of these sutures can have a host of consequences including increased risk for raised intracranial pressure, abnormal cranial shape, and distortion of craniofacial structures, which may affect breathing patterns, vision, and hearing. Moreover, syndromic forms of craniosynostosis may be characterized by other skeletal abnormalities and involvement of other organ systems. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182931210 ER -