TY - CHAP M1 - Book, Section TI - Acquired Hypothyroidism A1 - Bansal, Nidhi A1 - Athanassaki, Ioanna A2 - Kline, Mark W. Y1 - 2018 N1 - T2 - Rudolph's Pediatrics, 23e AB - Hypothyroidism is the most common thyroid abnormality in children. It can develop at any age among previously healthy children, although it is more common among girls. Growth retardation is an early sign. There are various causes of acquired hypothyroidism (Table 521-1). Iodine deficiency remains a major cause worldwide; however, the worldwide incidence is decreasing. Symptomatic iodine deficiency is uncommon in North America because of fortification of salt and the presence of iodine in dairy products. In the United States, acquired hypothyroidism is most often caused by autoimmune thyroiditis (Hashimoto thyroiditis) characterized by high levels of circulating antithyroid antibodies. Among other causes of acquired juvenile hypothyroidism are exposure to goitrogenic agents, thyroid dysgenesis, late onset of hypothyroidism caused by an inborn error of thyroidal biosynthesis, acquired hypothalamic or pituitary hypothyroidism, or endemic factors. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1182919387 ER -