TY - CHAP M1 - Book, Section TI - Chapter 304. Zygomycosis (Mucormycosis) A1 - Brady, Rebecca C. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. Y1 - 2011 N1 - T2 - Rudolph's Pediatrics, 22e AB - Zygomycosis is an umbrella term for all diseases caused by fungi of the class Zygomycetes. The more common term mucormycosis refers to a group of invasive mycoses caused by members of the order Mucorales within the class Zygomycetes.1Rhizopus species are the most commonly isolated agents of mucormycosis.2 The Mucorales are distributed worldwide and commonly grow in decaying organic matter.3 Although exposure to the airborne spores of these thermotolerant, rapidly growing fungi is universal, human disease is infrequent and is indicative of a serious underlying predisposing condition.4 Diabetes mellitus, particularly diabetic ketoacidosis, is the most common predisposing condition in patients with mucormycosis.2,5 Underlying disease accompanied by acidosis, such as uremia, malnutrition,6 and congenital metabolic aciduria,7 may also predispose to mucormycosis. Additional risk factors include neutropenia,8 hematological malignancies,9 burns,10 prematurity,11 corticosteroid therapy,12 solid-organ transplantation,13 bone marrow transplantation,14 and deferoxamine/desferrioxamine therapy for management of iron and aluminum overload states.15 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7029197 ER -