TY  - CHAP
M1  - Book, Section
TI  - Chapter 16. Inflammatory Bowel Disease
A1  - Scherr, Rebecca
A1  - Kugathasan, Subra
A2  - Bishop, Warren P.
Y1  - 2010
N1  - 
T2  - Pediatric Practice: Gastroenterology
AB  - In  a  day-to-day  practice,  general  pediatricians  are  expected  to  care  for  a  wide  variety  of  gastrointestinal  disorders.  Fortunately,  most  of  the  gastrointestinal  aliments  in  childhood  are  not  serious  and  self-limiting  in  nature  and  do  not  usually  require  a  referral  to  a  sub-specialty  such  as  pediatric  gastroenterology  with  few  exceptions.  Inflammatory  bowel  disease  (IBD)  is  an  exception;  consultation  with  a  pediatric  gastroenterologist  is  mandatory  for  adequate  management.  Crohn’s  disease  (CD)  and  ulcerative  colitis  (UC)  are  the  two  most  common  chronic  IBDs.  For  decades,  CD  and  UC  were  considered  totally  different  entities,  since  the  clinical  features,  treatment  options,  and  natural  history  of  these  diseases  appeared  to  be  quite  different.  However,  recent  developments  and  findings  have  made  clinicians  and  scientists  begin  to  think  of  IBD  as  one  entity,  with  a  spectrum  of  findings.  Recent  work  has,  for  example,  identified  CD  and  UC  occurring  in  the  same  families,  common  susceptibility  genes  and  pathways  between  these  two  entities,  and  similar  responses  to  emerging  therapies  to  both  conditions.  Classic  CD  is  found  at  one  end  of  the  spectrum  and  UC  at  the  other,  but  many  patients  have  features  that  overlap.  In  this  chapter,  we  will  try  to  approach  CD  and  UC  as  one  entity  but  differentiate  CD  from  UC  whenever  necessary.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=55941621
ER  -