TY - CHAP M1 - Book, Section TI - Chapter 33. Dermatology A1 - Lowry, Adam W. A1 - Bhakta, Kushal Y. A1 - Nag, Pratip K. Y1 - 2011 N1 - T2 - Texas Children's Hospital Handbook of Pediatrics and Neonatology AB - Table Graphic Jump Location|Download (.pdf)|PrintDiseaseDescriptionCourseTreatmentOtherErythema toxicumErythematous macules, papules, pustules, vesicles, or wheals on the face, torso, proximal limbs, and buttocksSpares palms and soles24–48 h after birth, may be seen ≤2 wk of ageResolve spontaneously and heal without sequelaeNoneAffects 50% of full-term neonatesEosinophils on Wright's stain of pustulesTransient neonatal pustular melanosisFragile, superficial pustules; no erythemaAfter rupture → collarette of scale and hyperpigmentationWidespread, including the palms and solesPresent at birthHyperpigmentation may last several monthsNoneAffects darker-skinned, full-term neonatesSterile subcorneal neutrophilic pustulesMiliaria crystallineSmall, flaccid vesicles on the forehead, neck, upper trunk, and occluded areasSometimes present at birthAvoid overheating and overswaddlingCaused by obstruction of eccrine sweat ducts near the surface of the skinMiliaria rubraSmall erythematous papules and pustules on the forehead, neck, upper trunk, and occluded areasUsually after first wk of lifeAvoid overheating and overswaddlingCaused by obstruction of eccrine sweat ducts in the deeper layer of the epidermisMilia1- to 2-mm white or yellow epidermoid cysts usually on the faceUsually resolve by age 1 moNoneIf seen on palate, known as Epstein's Pearls.Neonatal cephalic pustulosis (neonatal acne)Discrete, noncomedonal papules or pustules on an erythematous baseUsually on the cheeks; also on the forehead, chin, eyelids, neck, upper chest, and scalpOnset during first 2–3 wk of life; spontaneously resolves within weeksNone necessary; may be improved with topical clotrimazoleMay be caused by Malassezia spp.Acropustulosis of infancyCrops of acral, pruritic vesicles and pustules on the hands, wrists, feet, and anklesMay present in the neonatal period but usually at 3–6 mo of ageLast 1–2 wk and recur in 3–4 wkLess frequent relapses with age; complete resolution usually by age 3 yrTopical corticosteroids or oral antihistaminesIf severe, consider dapsoneSome pts respond to oral erythromycinMust exclude scabies (burrows, genital involvement); microscopic exam of scrapingNevus sebaceousHairless, thin, orange plaque on the scalp or face; may be seen on the neck or trunkProgressive thickening and a verrucous appearanceObservation; complete excision for cosmesis<1% develop secondary basal cell carcinomaCongenital melanocytic nevusTan or brown, oval plaques; sometimes hairyCommensurate growth with age; occasionally regressMay become verrucous with pigment changesYearly skin check for changesConsider bx and excision based on clinical changes, melanoma risk, location, age, and FHGiant nevi with greater risk of melanoma progressionNeurocutaneous melanocytosis with some larger scalp or axial lesionsNevus simplex or macular (vascular) stain (salmon patch, angel kiss, stork bite)Salmon pink, vascular patch commonly on the forehead, upper eyelids, or nape of the neckMay become more prominent with crying; blanches with pressureMost fade or resolve spontaneously, but neck lesions usually persistNone necessary; pulsed-dye laser for cosmesisMongolian spot (dermal melanocytosis)Bluish patches often on the lumbosacral or buttock areasSeen more commonly in patients with darker skin and AsiansMost fade with timeNoneDocument in newborn skin exam to avoid misdiagnosis of bruising or child abuseDiffuse or unusual distribution may suggest systemic involvement (eg, storage disease, phakomatosis pigmentovascularis) SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7450989 ER -