TY - CHAP M1 - Book, Section TI - Diabetes Mellitus and Hyperglycemia A1 - Ferrara, Christine T. A1 - Ackermann, Amanda M. A1 - Palladino, Andrew A. A2 - Zaoutis, Lisa B. A2 - Chiang, Vincent W. PY - 2017 T2 - Comprehensive Pediatric Hospital Medicine, 2e AB - Insulin is produced by beta cells in the islets of Langerhans in the pancreas. Insulin secretion is regulated by glucose influx into the beta cell, which is dependent on the serum glucose level. Insulin acts on target tissues including liver, fat, and muscle to stimulate glucose uptake and inhibit gluconeogenesis, glycogenolysis, lipolysis, and ketogenesis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1146116173 ER -