TY  - CHAP
M1  - Book, Section
TI  - Normal and Abnormal Hemostasis
A1  - Paredes, Nethnapha
A1  - Berry, Leslie R.
A1  - Chan, Anthony K. C.
A2  - Kline, Mark W.
PY  - 2018
T2  - Rudolph's Pediatrics, 23e
AB  - The  hemostatic  mechanism  is  a  dynamic  system  that  maintains  the  fluidity  of  blood  while  allowing  for  the  formation  of  blood  clots  to  prevent  bleeding  subsequent  to  blood  vessel  injury.  These  interrelated  components  consist  of  vessel  walls  (including  endothelial  cells),  platelets,  coagulation  factors,  inhibitors,  and  the  fibrinolytic  mechanism.  Perturbation  of  any  of  these  systems  can  lead  to  disease  states  that  are  thrombotic  or  hemorrhagic  in  nature.  This  chapter  discusses  the  normal  and  abnormal  hemostatic  system  in  children,  with  emphasis  on  disorders  involving  the  endothelium,  platelets,  and  defects  in  coagulation  and  fibrinolysis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1182910042
ER  -