TY - CHAP M1 - Book, Section TI - Chapter 449. Acute Lymphoblastic Leukemia A1 - Nachman, James B. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy, accounting for almost 25% of cancer diagnoses seen in children younger than age 15 years. Patients with more than 25% lymphoid blasts in the bone marrow are considered to have leukemia regardless of the presence of extramedullary disease. Patients who have an extramedullary lymphoid mass and 5% to 25% lymphoid blasts in the marrow are considered to have lymphoblastic lymphoma with marrow involvement. There are approximately 2400 new cases of ALL diagnosed in children and adolescents less than 20 years of age each year in the United States.1The peak incidence of ALL is in the 2- to 6-year-old age group. The incidence of ALL appears to be highest in Hispanic children and lowest in African American children.2 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7042265 ER -