TY  - CHAP
M1  - Book, Section
TI  - Diagnosis of Congenital Toxoplasmosis
A1  - McLeod, Rima
A1  - Lee, Daniel
A1  - Clouser, Fatima
A1  - Boyer, Kenneth
A2  - Stevenson, David K.
A2  - Cohen, Ronald S.
A2  - Sunshine, Philip
PY  - 2015
T2  - Neonatology: Clinical Practice and Procedures
AB  - Abundant  and  convincing  evidence  demonstrates  that  medicines  block  transmission  of  Toxoplasma  gondii  from  the  pregnant  woman  to  her  fetus,  kill  tachyzoites,  reduce  or  eliminate  parasite  burden,  reduce  or  eliminate  eye  disease,  reduce  or  eliminate  brain  disease,  reduce  severity  of  disease,  eliminate  meningitis,  treat  meningoencephalitis,  and  lower  immune  markers  of  infection.1,  2,  3,  and  4  Earlier,  there  was  some  controversy  in  the  literature  (discussed  in  Reference  4),  but  currently,  review  of  data  from  in  vitro  and  experimental  animal  studies,  attention  to  older  publications  of  studies  that  were  performed  meticulously  (reviewed  in  References  1,  2,  3,  and  4),  and  several  recent  studies  have  clarified  the  efficacy  and  benefits  of  proper,  early,  and  rapid  diagnosis  and  medical  treatment.5,6  The  recent  data  demonstrate  how  important  it  is  to  establish  such  diagnosis  and  treatment  as  the  standard  for  medical  care  to  prevent  the  loss  of  productive  lives  to  this  disease.  The  time  when  the  acute  infection  is  diagnosed  and  treated  is  critical.1,  2,  3,  4,  and  5  The  earlier  the  infection  is  treated,  the  better  the  outcomes  will  be  for  fetus,  infant,  and  congenitally  infected  person.5,6  For  this  reason,  the  focus  of  this  chapter  is  to  make  clear  how  diagnosis  and  treatment  of  the  fetus  and  infant  can  be  optimized  and  how  this  is  carried  out  practically.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1109799759
ER  -