RT Book, Section A1 Brady, Ken A1 Beca, John A2 Kline, Mark W. SR Print(0) ID 1182925282 T1 Acute Neurological Dysfunction T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182925282 RD 2024/04/20 AB Altered consciousness can be a manifestation of a variety of disease processes. It is commonly indicative of life-threatening illness that requires urgent stabilization, diagnosis, and institution of disease-specific therapy to prevent ongoing neurologic injury and long-term neurodevelopmental disability. Although the anatomic structures related to consciousness have been defined, depressed consciousness is usually poorly localized to specific nervous system pathways, and often represents the consequence of a failed non-neurologic organ system.