RT Book, Section
A1 Hay, Jr, William W.
A1 Levin, Myron J.
A1 Deterding, Robin R.
A1 Abzug, Mark J.
SR Print(0)
ID 1145456769
T1 Leukemia, Acute Myeloid (AML)
T2 Quick Medical Diagnosis & Treatment Pediatrics
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781264257614
LK accesspediatrics.mhmedical.com/content.aspx?aid=1145456769
RD 2024/04/19
AB Approximately  500  new  cases  occur  per  year  in  children  and  adolescents  in  the  United  StatesAlthough  AML  accounts  for  only  25%  of  all  leukemias  in  this  age  group,  it  is  responsible  for  at  least  one-third  of  deaths  from  leukemia  in  children  and  teenagersCongenital  conditions  associated  with  an  increased  risk  of  AML  includeDiamond-Blackfan  anemiaNeurofibromatosisDown  syndromeWiskott-Aldrich,  KostmannLi-Fraumeni  syndromesChromosomal  instability  syndromes  such  as  Fanconi  anemiaAcquired  risk  factors  include  exposure  to  ionizing  radiation,  cytotoxic  chemotherapeutic  agents,  and  benzenesHowever,  the  vast  majority  of  patients  have  no  identifiable  risk  factors