RT Book, Section A1 Hay, Jr, William W. A1 Levin, Myron J. A1 Deterding, Robin R. A1 Abzug, Mark J. SR Print(0) ID 1145458113 T1 Precocious Puberty in Girls T2 Quick Medical Diagnosis & Treatment Pediatrics YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781264257614 LK accesspediatrics.mhmedical.com/content.aspx?aid=1145458113 RD 2024/04/23 AB Defined as pubertal development occurring below the age limit set for normal onset of pubertyMore common in girls than in boysMany girls showing signs of puberty between 6 and 8 years of age have a benign, slowly progressing form that requires no interventionAge of pubertal onset may be advanced by obesityCentral precocious puberty in girls is generally idiopathic but may be secondary to a central nervous system (CNS) abnormalities, including but not limited toHypothalamic hamartomasCNS tumorsCranial irradiationHydrocephalusTraumaPeripheral precocious puberty (GnRH-independent)Occurs independent of gonadotropin secretionCan be caused by ovarian or adrenal tumors, ovarian cysts, late-onset congenital adrenal hyperplasia, McCune-Albright syndrome, or exposure to exogenous estrogen