RT Book, Section
A1 Hay, Jr, William W.
A1 Levin, Myron J.
A1 Deterding, Robin R.
A1 Abzug, Mark J.
SR Print(0)
ID 1145458187
T1 Pulmonary Hypertension, Persistent
T2 Quick Medical Diagnosis & Treatment Pediatrics
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781264257614
LK accesspediatrics.mhmedical.com/content.aspx?aid=1145458187
RD 2024/04/25
AB Onset  of  symptoms  on  day  1  of  lifeHypoxia  with  poor  response  to  high  concentrations  of  inspired  oxygenRight-to-left  shunts  through  the  foramen  ovale,  ductus  arteriosus,  or  bothMost  often  associated  with  parenchymal  lung  diseaseThere  are  three  underlying  pathophysiologic  mechanismsVasoconstriction  due  to  perinatal  hypoxia  related  to  an  acute  event  such  as  sepsis  or  asphyxiaPrenatal  increase  in  pulmonary  vascular  smooth  muscle  development,  often  associated  with  meconium  aspiration  syndromeDecreased  cross-sectional  area  of  the  pulmonary  vascular  bed  associated  with  lung  hypoplasia  (eg,  diaphragmatic  hernia)