RT Book, Section
A1 Chow, Eric J.
A1 Armenian, Saro
A2 Kline, Mark W.
SR Print(0)
ID 1182911046
T1 Cancer Survivorship and Recommendations for Follow-Up
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182911046
RD 2024/04/24
AB Five-year  survival  rates  for  childhood  cancer  now  exceed  80%.  This  has  resulted  in  a  growing  population  of  childhood  cancer  survivors—there  are  nearly  half  a  million  such  survivors  in  the  United  States  today.  Cancer  and  its  treatment  during  childhood  can  result  in  a  variety  of  long-term  sequelae,  such  as  impairment  in  growth  and  development,  endocrine  dysfunction,  neurocognitive  issues,  cardiopulmonary  compromise,  and  subsequent  malignancies  (Table  444-1).  These  sequelae  are  primarily  related  to  specific  therapeutic  exposures,  with  important  effects  on  both  the  overall  quality  of  life  (QOL),  as  well  as  in  some  cases,  potential  life  expectancy  of  survivors.  Approximately  two-thirds  of  the  survivors  will  experience  at  least  1  chronic  medical  problem,  and  about  one-third  will  experience  a  late  effect  that  is  severe  or  life  threatening.  However,  over  time,  as  cancer  treatment  has  improved,  we  may  see  a  decrease  in  late  mortality  and  morbidity.