RT Book, Section
A1 Janeway, Katherine A.
A1 Gorlick, Richard
A2 Kline, Mark W.
SR Print(0)
ID 1182911310
T1 Osteosarcoma
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182911310
RD 2024/04/19
AB Osteosarcoma  should  be  considered  in  the  differential  diagnosis  of  bone  pain,  as  early  recognition  may  increase  the  likelihood  that  radiographically  visible  metastatic  disease,  which  adversely  impacts  patient  prognosis,  will  not  develop  between  the  time  of  symptom  onset  and  diagnosis.  In  addition  to  its  importance  as  a  clinical  entity,  its  rigorous  study,  beginning  with  an  osteosarcoma  registry  created  under  the  auspices  of  the  American  College  of  Surgeons  in  1921,  highlights  important  oncologic  principles,  including  the  concept  of  microscopic  metastatic  disease  and  the  role  of  adjuvant  therapy.