RT Book, Section
A1 Koeller, David M.
A2 Kline, Mark W.
SR Print(0)
ID 1182928542
T1 Disorders of Metabolism of Lysine and Related Compounds
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182928542
RD 2024/04/25
AB Lysine  is  an  essential  amino  acid  that  can  be  degraded  via  2  alternative  pathways.  The  predominant  route  is  via  the  saccharopine  pathway,  with  the  peroxisomal  pipecolic  acid  pathway  playing  a  relatively  minor  role.  Degradation  of  lysine  through  either  pathway  leads  to  the  formation  of  α-aminoadipic  semialdehyde,  which  is  catabolized  to  acetyl-coenzyme  A  (CoA)  and  enters  the  tricarboxylic  acid  (TCA)  cycle.