RT Book, Section
A1 Diaz, Lucia Z.
A1 Levy, Moise L.
A2 Kline, Mark W.
SR Print(0)
ID 1182905035
T1 Neonatal Dermatology
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182905035
RD 2024/04/23
AB The  skin  of  a  newborn  infant  differs  from  adult  skin  in  several  ways  that  place  infants  at  increased  risk  for  thermal  instability,  skin  damage,  percutaneous  infection,  and  percutaneous  toxicity  from  topically  applied  agents.  The  neonatal  body  surface  area–to–weight  ratio  is  far  greater  than  that  of  an  adult  with  thinner  skin  overall.  Sebaceous  glands  are  hypertrophic  for  several  weeks  after  birth,  under  the  influence  of  fetal  and  maternal  androgens,  but  eccrine  function  does  not  mature  until  after  term,  placing  newborns  at  risk  for  hyperthermia  with  overbundling.  The  vernix  caseosa  is  composed  of  sloughed  keratinocyte  and  sebaceous  gland  lipids,  with  a  higher  proportion  of  glandular  lipids  in  males.