RT Book, Section A1 Erdman, Steven H. A1 Hoffenberg, Edward J. A2 Kline, Mark W. SR Print(0) ID 1182908716 T1 Polyps and Tumors of the Gastrointestinal Tract T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182908716 RD 2024/04/20 AB The most common gastrointestinal tumor in children is the benign single juvenile polyp. Juvenile polyps are relatively common and do not infer an increased risk of colorectal cancer at any age. In contrast, findings of 5 or more hamartomatous polyps, 1 or more adenomas, polyps of multiple histologic types, or abnormal dysplastic histology suggest a hereditary or genetic cancer predisposition syndrome that can include cancers of multiple organ systems. A family history of colon cancer under the age of 50 years and/or gastrointestinal polyps affecting multiple relatives over several generations warrants evaluation for the presence of a hereditary cancer syndrome.