RT Book, Section A1 Larson, Charles A1 Guerguerian, Anne-Marie A1 Butt, Warwick A2 Kline, Mark W. SR Print(0) ID 1182925899 T1 Management of Acute Brain Injury T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182925899 RD 2024/04/19 AB Primary etiologies of acute brain injury in children include traumatic brain injury (TBI), hypoxic-ischemic encephalopathy (HIE), stroke, cerebral hemorrhages, infections, inflammatory conditions, seizures, tumor or mass lesions, metabolic abnormalities, and toxins (Table 105-1). TBI is the leading cause of death and disability in both children older than 1 year of age and young adults. Following the primary injury, the tissues surrounding the injury and the entire brain are vulnerable to further secondary injuries. The purpose of the initial management, investigation, monitoring, and treatment of acute brain injuries is aimed at preventing this secondary injury.