RT Book, Section
A1 Patel, Ravi Mangal
A1 Neu, Josef
A2 Kline, Mark W.
SR Print(0)
ID 1182921777
T1 Necrotizing Enterocolitis
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182921777
RD 2024/04/25
AB Necrotizing  enterocolitis  (NEC)  is  a  serious  gastrointestinal  disease  that  occurs  primarily  in  preterm  infants.  The  disease  is  characterized  by  the  rapid  onset  of  intestinal  inflammation  and,  in  severe  cases,  can  lead  to  intestinal  necrosis  and  multiorgan  dysfunction  that  results  in  death.  Since  the  1950s,  when  neonatal  intensive  care  was  introduced  at  many  centers  around  the  world  with  survival  of  very  low–birth-weight  (VLBW)  infants,  NEC  has  been  reported  as  a  complication  of  premature  birth.  It  remains  the  most  common  gastrointestinal  complication  in  preterm  infants,  and  is  a  major  cause  of  morbidity  and  mortality  in  neonates,  accounting  for  10%  of  deaths  in  the  neonatal  intensive  care  unit  (NICU).  Reports  from  the  United  States,  the  United  Kingdom,  Sweden,  and  the  Netherlands  indicate  that  NEC  is  increasing  as  a  cause  of  death,  as  survival  from  lung  disease  has  improved  for  preterm  infants.