RT Book, Section
A1 Woodbury, Suzanne L.
A1 Collier, Talia
A2 Kline, Mark W.
SR Print(0)
ID 1182924023
T1 Peripheral Nerve Disorders and Anterior Horn Cell Diseases
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182924023
RD 2024/04/19
AB Diseases  affecting  the  lower  motor  and  sensory  neurons  can  be  classified  by  the  area  of  pathologic  involvement  and  are  divided  into  2  groups:  anterior  horn  cell  diseases  and  peripheral  nerve  disorders.  Anterior  horn  cell  (also  known  as  motor  neuron)  diseases  affect  the  most  proximal  portion  of  the  motor  unit  and  are  primarily  inherited  or  infectious.  The  spinal  muscular  atrophies  are  the  major  inherited  disorders  of  the  anterior  horn  cell.  Infectious  anterior  horn  cells  disorders  include  paralytic  poliomyelitis,  which  is  largely  eradicated  from  the  Western  world,  in  addition  to  other  enterovirus,  arbovirus,  and  West  Nile  virus.  Peripheral  nerve  disorders  affect  the  nerve  segments  distal  to  the  anterior  horn  cell  and  may  be  divided  into  hereditary  neuropathies  and  acquired  neuropathies.  Hereditary  neuropathies  (Charcot-Marie-Tooth)  are  more  common  in  children  than  are  acquired  neuropathies.  Acquired  neuropathies  include  autoimmune  inflammatory  neuropathies  such  as  Guillain-Barre  syndrome  and  chronic  inflammatory  demyelinating  polyneuropathy,  facial  neuropathies,  infectious  neuropathies,  traumatic  neuropathies,  perinatal  brachial  plexus  injuries,  toxic  neuropathies,  and  vitamin  deficiency  neuropathies.