RT Book, Section A1 Harper, Marvin B. A2 Shah, Samir S. SR Print(0) ID 6903048 T1 Chapter 16. Meningitis T2 Pediatric Practice: Infectious Disease YR 2009 FD 2009 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-148924-9 LK accesspediatrics.mhmedical.com/content.aspx?aid=6903048 RD 2024/04/20 AB Meningitis is defined as an inflammation of the leptomeninges of any cause. Bacteria, which cause meningitis by invading and replicating in the subarachnoid space, are associated with significant morbidity and mortality. Viral infections may also cause meningitis, most commonly enteroviruses, but few children with viral meningitis suffer any long-term sequelae. Therefore, the focus of this chapter will be on bacterial meningitis. Figure 16–1 displays the age and organism-specific rates of bacterial meningitis in the United States prior to the introduction of currently used conjugate vaccines (note the y-axis is a log scale). As can be seen, the greatest risk period for bacterial meningitis is in the first 6 months of life.