RT Book, Section A1 Breland, David J. A1 Rubinstein, Mark L. A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 6736839 T1 Chapter 65. Reproductive Growth and Development in the Male Adolescent T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=6736839 RD 2024/04/19 AB Testicular growth and maturation are largely influenced by testosterone, which is produced by the testicle both before and after birth.1 Testosterone production is regulated centrally by the hypothalamic-pituitary-testicular axis as well as intragonadally. Testosterone effects include embryologic male genital differentiation, neonatal imprinting of androgen-dependent target tissue, maturation of the genitalia at puberty, growth of skeletal muscle, deepening of the voice from laryngeal growth, epiphyseal cartilage growth during puberty, male hair growth and distribution, erythropoiesis, stimulation of sebaceous glands, and male social behavior.1,2