RT Book, Section
A1 Smith, Jodi M.
A1 Mcdonald, Ruth A.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 6723444
T1 Chapter 129. Kidney Transplantation
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=6723444
RD 2024/04/19
AB Pediatric  end-stage  renal  disease  is  successfully  managed  with  either  chronic  dialysis  or  renal  transplantation  (see  Chapters  477  and  478).  Because  transplantation  promotes  more  normal  growth  and  development  compared  with  chronic  dialysis,  it  is  now  the  preferred  approach  to  management.1,2  However,  the  required  chronic  immunosuppression  exposes  children  to  multiple  complications  and  side  effects  (see  Chapter  128),  so  management  strategies  attempt  to  minimize  or  eliminate  immunosuppression  while  assuring  graft  survival.  Many  factors  determine  the  optimal  time  for  transplant  in  the  individual  patient,  including  the  patient  age,  primary  renal  disease,  psychosocial  status,  family  dynamics,  availability  of  a  living  donor  versus  deceased  donor  allograft,  optimal  immunosuppressive  therapy,  and  maximization  of  growth  and  development.