RT Book, Section
A1 Woolfrey, Ann E.
A1 Carpenter, Paul A.
A1 Sanders, Jean E.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 6723823
T1 Chapter 133. Hematopoietic Cell Transplantation
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=6723823
RD 2024/04/23
AB Hematopoietic  cell  transplantation  (HCT)  transfers  a  small  number  of  hematopoietic  stem  cells  (HSC)  from  a  donor  to  a  recipient,  where  they  are  able  to  differentiate  and  proliferate  to  restore  a  normal  hematopoietic  and  immune  system  (see  eFig.  133.1).  HCT  is  performed  in  patients  with  life-threatening  hematologic  disorders  or  as  a  means  to  restore  hematopoietic  function  following  administration  of  otherwise  lethal  doses  of  chemotherapy  or  radiation  for  treatment  of  resistant  malignancies.  HCT  also  has  the  potential  to  cure  disorders  resulting  from  defects  in  the  pluripotent  progenitor  cells  or  in  a  single  hematopoietic  lineage.