RT Book, Section
A1 Goodman, Stephen I.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 6726044
T1 Chapter 153. Disorders of Leukotriene Synthesis and Fatty Aldehyde Dehydrogenase
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=6726044
RD 2024/04/19
AB Leukotrienes  are  lipids  derived  from  20-carbon  polyunsaturated  fatty  acids  and  are  best  known  as  mediators  of  inflammation.  They  are  synthesized  in  many  tissues,  including  the  brain,  and  have  a  very  short  half-life  in  vivo.  Two  disorders  are  known  in  which  biosynthesis  is  defective.  Another  disorder,  Sjögren-Larsson  syndrome,  appears  to  be  due  to  impaired  leukotriene  degradation.