RT Book, Section
A1 Riedel, Marc A.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 7018791
T1 Chapter 197. Adverse Reactions to Drugs
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=7018791
RD 2024/04/23
AB Drug  reactions  encompass  all  adverse  events  related  to  drug  administration,  regardless  of  etiology.1  While  adverse  drug  reactions  are  common,  only  a  small  portion  of  these  represent  drug  hypersensitivity,  defined  as  an  immunologically-mediated  response  to  a  drug  agent  in  a  sensitized  patient.  In  turn,  only  a  subset  of  drug  hypersensitivity  reactions  represent  a  true  drug  allergy,  which  refers  specifically  to  a  reaction  mediated  by  IgE.2  These  distinctions  are  important  for  optimal  patient  management,  risk  assessment,  and  education  of  patients  regarding  specific  drug  reactions.