RT Book, Section A1 Murray, Thomas S. A1 Baltimore, Robert S. A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7022283 T1 Chapter 231. Bacterial Infections of the Central Nervous System T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7022283 RD 2024/04/19 AB Meningitis, an infection of the subarachnoid space and leptomeninges caused by a variety of pathogenic organisms, continues to be an important source of mortality and morbidity. Despite the introduction of new vaccines that prevent the most severe causes, bacterial, or purulent, meningitis remains the most important form in the United States in terms of incidence, sequelae, and ultimate loss of productive life. Aseptic meningitis, usually caused by viruses, especially enteroviruses (see Chapter 306) is more common; however, significant sequelae are uncommon and the disease is usually self-limited. Granulomatous meningitis, caused either by M tuberculosis or fungi, is a major cause of neurologic injury and death in the developing world (See Chapter 269).