RT Book, Section
A1 Shehab, Ziad M.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 7026002
T1 Chapter 266. Listeriosis
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=7026002
RD 2024/04/20
AB Listeria  monocytogenes  is  a  food-borne  pathogen  that  causes  disease  primarily  in  neonates,  pregnant  women,  the  elderly,  and  the  immunocompromised  host.1  It  is  worldwide  in  distribution  and  is  acquired  relatively  frequently  in  developed  countries  due  to  consumption  of  refrigerated,  contaminated,  ready-to-eat  food,  mostly  dairy  products  and  cold  cuts.2  Listeriosis  is  a  zoonosis  of  many  animal  species.  In  humans,  it  causes  epidemic  and  sometimes  sporadic  outbreaks  of  febrile  gastroenteritis.3  Systemic  infection  results  from  passage  of  the  organism  across  the  intestinal  mucosal  barrier  by  endocytosis,  coupled  with  its  ability  to  evade  immune  surveillance  by  cell-to-cell  spread;  deficiencies  in  T-cell  immunity  such  as  in  pregnancy  and  immunosuppression  increase  the  risk  of  listeriosis.4,5  Extraintestinal  disease  results  from  hematogenous  dissemination  with  particular  predilection  for  central  nervous  system  and  placental  infections.