RT Book, Section A1 Rosenblum, Norman D. A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7045045 T1 Chapter 469. Renal Malformations T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7045045 RD 2024/04/23 AB Renal malformations account for 30% to 50% of end-stage renal disease in children. Approximately one half of such cases are associated with lower urinary tract abnormalities. A spectrum of phenotypes exists and has been termed CAKUT (congenital abnormalities of the kidney and urinary tract). This chapter focuses on the epidemiology of these abnormalities and their etiologies, clinical manifestations, and aspects of clinical management.