RT Book, Section A1 Pasterkamp, Hans A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7050182 T1 Chapter 505. Clinical Presentation of Respiratory Illness T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7050182 RD 2024/04/25 AB Respiratory illness in children usually presents with clinical symptoms and signs that offer important information for further diagnostic tests. The primary function of the respiratory system is to provide a supply of oxygen and removal of carbon dioxide, that is, adequate and adaptive gas exchange. Illness can disturb this function by affecting respiratory control, the respiratory pump, that is, chest cage and respiratory muscles, airways, and the pulmonary tissues. The many nonrespiratory functions of the lung include production and regulation of surfactant, defense against infections, participation in water and fluid balance, sieving of blood cells and emboli, and elimination of volatile substances. The clinical presentation of illness interfering with these functions is often related to the secondary effects on respiratory mechanics and gas exchange.