RT Book, Section
A1 Fisher, Delbert A.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 7053228
T1 Chapter 527. Hypothyroidism in the Infant
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=7053228
RD 2024/04/24
AB Causes  of  hypothyroidism  are  listed  in  Table  527-1.  Transient  neonatal  hypothyroidism  occurs  in  premature  infants,  and  may  be  caused  by  drugs  or  maternal  antibodies.  The  most  common  cause  of  nonendemic  congenital  hypothyroidism  is  defective  thyroid  embryogenesis.  Inborn  defects  in  thyroid  hormone  synthesis  or  action  are  the  second  most  common  cause  of  congenital  hypothyroidism.1-13  Other  causes  include  intrauterine  exposure  to  goitrogenic  agents  and  hypothalamic-pituitary  disorders.  These  usually  occur  in  the  setting  of  panhypopituitarism,  but  isolated  defects  in  thyrotropin-releasing  hormone  (TRH)  or  thyroid-stimulating  hormone  (TSH)  do  occur.5-7