RT Book, Section A1 Khwaja, Omar A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7056466 T1 Chapter 548. Cranial Developmental Abnormalities T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7056466 RD 2024/04/24 AB The central nervous system (CNS) is the most complex organ in the human body comprising a highly organized anatomic scaffold of billions of cells and a network of trillions of connections. Structural brain development proceeds through an integrated series of often rapid developmental events from early embryogenesis through fetal life and into early adulthood. It is therefore not surprising that many common childhood neurologic and developmental disorders have their origins in genetic or environmental perturbations of embryonic or fetal brain development.