RT Book, Section
A1 Weinberg, Samuel
A1 Prose, Neil S.
A1 Kristal, Leonard
SR Print(0)
ID 6987932
T1 Section 11. Genodermatoses
T2 Color Atlas of Pediatric Dermatology, 4e
YR 2008
FD 2008
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-145543-5
LK accesspediatrics.mhmedical.com/content.aspx?aid=6987932
RD 2024/04/19
AB This  is  a  generalized  condition  in  which  elastic  fibers  are  degenerative.  Clinical  signs  of  the  phenomenon  can  be  recognized  in  the  skin  and  eyes.  In  the  skin,  patches  of  yellowish  discoloration  and  general  laxness  or  redundancy  develop  on  the  neck  (“chicken  skin”),  in  the  axillae,  and  in  other  places,  such  as  the  fossae  of  limbs  and  the  inguinal  folds,  where  considerable  movement  of  skin  is  normal.  In  the  eye,  the  so-called  angioid  streaks  can  be  seen.  They  represent  the  result  of  faulty  elastic  fibers  in  Bruch's  membrane  and  generally  precede  the  cutaneous  changes.  These  eye  changes  frequently  result  in  the  loss  of  central  vision  and  sometimes  result  in  almost  complete  peripheral  vision  is  maintained  blindness.