RT Book, Section
A1 Mousa, Hayat
A2 Bishop, Warren P.
SR Print(0)
ID 55942210
T1 Chapter 19. Disorders of Gastrointestinal Motility
T2 Pediatric Practice: Gastroenterology
YR 2010
FD 2010
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-163379-6
LK accesspediatrics.mhmedical.com/content.aspx?aid=55942210
RD 2024/04/23
AB Gastrointestinal  (GI)  motility  disorders  (GMDs)  are  represented  by  a  spectrum  of  conditions  that  range  from  benign  prevalent  disorders  (gastroesophageal  reflux  (GER)  and  childhood  constipation)  to  more  rare  and  severe  entities  (chronic  intestinal  pseudo-obstruction  (CIP)  and  Hirschsprung’s  disease).  Altered  GI  motility  adds  considerable  co-morbidity  to  structural  anomalies  such  as  intestinal  atresia,  stenosis,  or  gastroschisis.  Pediatric  GMDs  are  classified  according  to  the  results  of  GI  motility  testing.  It  is  likely  that  with  advanced  methods  of  studying  the  brain–gut  axis,  classification  of  these  disorders  will  eventually  be  based  on  pathophysiology.  Within  the  pediatric  population,  GMDs  are  also  known  to  be  either  congenital  or  acquired,  depending  on  the  presence  or  absence  of  symptoms  at  birth.1,2  Congenital  disorders  usually  cause  symptoms  within  the  first  2  months  of  life  and  can  be  sporadic  or  familial.  Acquired  motility  disorders  present  later  in  life  and  can  be  secondary  to  a  variety  of  insults  including  infections  and  adverse  reactions  to  medications.3  Within  the  pediatric  population,  GMDs  account  for  up  to  15%  of  all  intestinal  failures.