RT Book, Section A1 Mileti, Elizabeth A1 Rosenthal, Philip A2 Bishop, Warren P. SR Print(0) ID 55944062 T1 Chapter 30. Liver Failure and Portal Hypertension T2 Pediatric Practice: Gastroenterology YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-163379-6 LK accesspediatrics.mhmedical.com/content.aspx?aid=55944062 RD 2024/04/24 AB Acute liver failure (ALF) is a rare but devastating result of hepatic necrosis in previously healthy individuals. Hepatic function rapidly declines within days to weeks and is often complicated by coagulopathy, hepatic encephalopathy (HE), hypoglycemia, acute renal failure, sepsis, and gastrointestinal bleeding. These complications can lead to death with mortality rates up to 40% in the United States.1