RT Book, Section A1 Stevenson, David K. A1 Vreman, Hendrik J. A1 Wong, Ronald J. A2 Stevenson, David K. A2 Maisels, M. Jeffrey A2 Watchko, Jon F. SR Print(0) ID 56321432 T1 Chapter 2. Bilirubin Production and Its Measurement T2 Care of the Jaundiced Neonate YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176289-2 LK accesspediatrics.mhmedical.com/content.aspx?aid=56321432 RD 2024/04/20 AB Neonatal jaundice is one of the first and perhaps the most common problem encountered by the practicing pediatrician. It is a natural phenomenon occurring in the majority of full-term infants and virtually in all preterm infants.1,2 Neonatal jaundice reflects the presence of pigment in the skin and sclera, although little is known about the exact location of the pigment and to what it might be bound in those locations.3 Nonetheless, it is related to hyperbilirubinemia in the transition after birth, which occurs in all babies, except those lacking albumin, which is an extremely rare condition. This transitional phenomenon is usually benign and may have a physiological role in development, but under some conditions bilirubin outside the circulation can be dangerous, such as its accumulation in the brain, contributing to neurologic dysfunction and, sometimes, permanent injury.1,4