RT Book, Section
A1 Gomella, Tricia Lacy
A1 Cunningham, M. Douglas
A1 Eyal, Fabien G.
A1 Tuttle, Deborah J.
SR Print(0)
ID 1107528465
T1 Common Multiple Congenital Anomaly Syndromes
T2 Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e
YR 2013
FD 2013
PB McGraw-Hill Education
PP New York, NY
SN 9780071768016
LK accesspediatrics.mhmedical.com/content.aspx?aid=1107528465
RD 2024/04/25
AB A  congenital  anomaly  is  defined  as  a  structural  defect,  present  at  birth  and  different  from  the  norm.  These  anomalies  can  be  further  divided  into  major  anomalies  that  require  medical  and  surgical  care  (eg,  congenital  heart  defect,  cleft  palate,  meningomyelocele)  and  minor  anomalies  that  do  not  have  medical  significance  (eg,  single  palmar  crease,  epicanthal  folds,  fifth  digit  clinodactyly).  Anomalies  themselves  can  be  classified  based  on  the  developmental  process  involved  in  their  formation.  Well-defined  types  of  anomalies  include  malformations,  deformations,  disruptions,  dysplasias,  syndromes,  associations,  and  sequences  (Table  89–1).  It  is  also  important  to  understand  that  these  may  not  be  entirely  mutually  exclusive.  Table  89–1  provides  an  overview  of  congenital  anomalies  that  are  associated  with  congenital  heart  disease,  and  Table  89–2  reviews  the  teratogens  associated  with  some  of  these  lesions.