RT Book, Section
A1 Wells, Robert G.
SR Print(0)
ID 1148949704
T1 Intracranial Neoplasms and Masses
T2 Diagnostic Imaging of Infants and Children
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071808392
LK accesspediatrics.mhmedical.com/content.aspx?aid=1148949704
RD 2024/04/25
AB The  central  nervous  system  (CNS)  is  the  site  of  origin  for  approximately  20%  of  pediatric  cancers.  CNS  neoplasms  are  the  second  most  common  type  of  childhood  tumors,  after  leukemia.  The  overall  5-year  survival  rate  for  pediatric  CNS  malignancies  is  70%.  The  prevalence  of  brain  tumors  in  children  younger  than  15  years  of  age  is  approximately  2.4  per  100,000.  High-grade  (World  Health  Organization  [WHO]  grade  ≥3)  CNS  neoplasms  in  children  include  primitive  neuroectodermal  tumor  (PNET),  malignant  germ  cell  tumors,  grade  III/IV  astrocytoma,  leukemia/lymphoma,  esthesioneuroblastoma,  and  metastatic  disease.  Low-grade  (WHO  grade  ≤2)  tumors  include  juvenile  pilocytic  astrocytoma,  grade  II  astrocytoma,  germinoma,  craniopharyngioma,  meningioma,  ganglioglioma,  nonanaplastic  ependymoma,  acoustic  neuroma,  low-grade  oligodendroglioma,  and  dysembryoplastic  neuroepithelial  tumor  (DNET).1