Procainamide | Ia | IV: Loading dose: 10–15 mg/kg over 30–60 min; in adults, maximum dose range: 1000–1500 mg Maintenance: Continuous IV infusion: 20–80 mcg/kg/minute; maximum daily dose: 2000 mg/24 hr | Decreases atrial and ventricular automaticity, vagolytic effect |
Lidocaine | Ib | | Affects ventricular tissue |
Mexiletine | |
Phenytoin | |
Flecainide | Ic | | Slows conduction velocities throughout the myocardium |
Propafenone | |
Esmolol | II | | Lowers heart rate, decreases automaticity, slows AV nodal conduction |
Propranolol | |
Metoprolol | |
Ibutilide | III | | Prolongs repolarization and refractoriness of atrial, nodal, and ventricular tissue |
Sotalol | | |
Amiodarone | | |
Verapamil | IV | | Slows conduction in sinus and AV nodes |
Diltiazem | |
Digoxin | Misc | | Directly suppresses AV node conduction |
Adenosine | Misc | | |
Magnesium | Misc | | |
Atropine | Misc | | |
Isoproterenol | Misc | | |